Multiple sites of calciphylaxis in a patient with chronic renal failure

Autor: Ramy Magdy Hanna, Joseph Riad Nabil, Eduardo A Lopez, Dalila B Corry, James Wilson
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Saudi Journal of Kidney Diseases and Transplantation, Vol 26, Iss 2, Pp 344-348 (2015)
Druh dokumentu: article
ISSN: 1319-2442
DOI: 10.4103/1319-2442.152506
Popis: Calciphylaxis has seldom been reported in patients with acute renal failure or in pre-dialysis patients. It also has been reported at lower calcium phosphorous products and in patients with adynamic bone disease. We report a pre-hemodialysis (HD) patient with acute renal failure and biopsy-proven calciphylaxis involving multiple cutaneous sites with calcification of the perineal area resulting in dry gangrene of the penis that necessitated a partial penectomy. The patient had elevated serum calcium, phosphorous and parathyroid hormone level of 612 pg/mL. The same patient suffered subsequently from a calcium embolus that occluded his left ophthalmic artery and resulted in left eye blindness. Calciphylaxis is a devastating phenomenon and physicians should have a high clinical suspicion for it in HD patients as well as in patients with late stages of chronic kidney disease.
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