Effective Endoscopic Submucosal Dissection of a Huge Esophageal Liposarcoma: A Case Report

Autor: Myeong Jin Lee, Moon Won Lee, Dong Chan Joo, Seung Min Hong, Dong Hoon Baek, Bong Eun Lee, Gwang Ha Kim, Geun Am Song
Jazyk: English<br />Korean
Rok vydání: 2024
Předmět:
Zdroj: The Korean Journal of Gastroenterology, Vol 83, Iss 6, Pp 243-246 (2024)
Druh dokumentu: article
ISSN: 1598-9992
2233-6869
DOI: 10.4166/kjg.2024.047
Popis: This case report presents the successful endoscopic submucosal dissection (ESD) of a well-differentiated esophageal liposarcoma in a 51-year-old male with persistent dysphagia. The cause was initially diagnosed as a 10 cm pedunculated lesion extending from the upper esophageal sphincter to the mid-esophagus. An ESD was chosen over traditional surgery because it is less invasive. The procedure involved a precise submucosal injection and excision with special techniques to manage bleeding from a central vessel. Despite the extraction challenges owing to the size of the lesion, it was successfully removed orally. A histopathological examination of the 8.3×4.2×2.3 cm specimen revealed the characteristic features of a well-differentiated liposarcoma, including MDM2 and CDK4 positivity. The follow-up revealed no recurrence, and active surveillance has been performed since. This report highlights the versatility of ESD in treating significant esophageal tumors and provides evidence for its efficacy as a minimally invasive alternative.
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