Safety and feasibility of same day discharge after per oral endoscopic pyloromyotomy in refractory gastroparesis: a pilot study

Autor: Rushikesh Shah, Huimin Chen, Lucie F. Calderon, Tonia Gooden, Maryam Mubashir, Shazia Rashid, Syed Musa Raza, Allison Derise, Grace Mccurdy, Brenna Sanders, Steve Keilin, Qiang Cai, Yanjie Yin
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Chinese Medical Journal, Vol 135, Iss 12, Pp 1432-1437 (2022)
Druh dokumentu: article
ISSN: 0366-6999
2542-5641
00000000
84802901
DOI: 10.1097/CM9.0000000000002068
Popis: Abstract. Background:. Gastroparesis is a debilitating medical condition with limited treatment options. Gastric per-oral pyloromyotomy (G-POEM) has emerged as a promising treatment option with remarkable short-term clinical success shown in multiple studies. While the post-procedure protocol is not standardized across many centers, the majority of the centers observes these patients in the hospital after the procedure for monitoring. In this single-center prospective study, we evaluated the safety and feasibility of same day discharge after the G-POEM procedure. Methods:. All the patients with refractory gastroparesis undergoing G-POEM from October 2019 to March 2020 were enrolled. A total of 25 patients were enrolled in the procedure. Based on the pre-defined criteria, patients were either discharged on the same day after the procedure or admitted to the hospital for further observation. The patient and procedure-related data were extracted from the chart review. Univariate analysis was performed (chi-squared test) on categorical variables after organizing categorical variables as numeric counts or percentages. The student t test was performed on continuous variables after reporting as mean and standard deviation. For analysis with a smaller sample size, Fisher exact and Mann–Whitney tests were used. Results:. A total of 25 patients were enrolled. The technical success of G-POEM was 100% and clinical success was 80% (20/25) at 1-month follow-up. Of the 25 patients, 9 patients (36%) were discharged on the same day according to the procedure from the recovery unit. Of the remaining 16 patients who were admitted to the hospital post-procedure, 10 (40%) were admitted due to procedure-related causes while other admissions were either pre-planned or due to social reasons. The average Charlson comorbidity index was lower in the same day discharge group (P 50% of patients with close periprocedural monitoring.
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