Efficacy of four different hemostatic agents in thyroid surgery in reducing the amount of post-operative fluid collection

Autor: Thomas von Ahnen, Martin von Ahnen, Sonja Militz-Müller, Anna Süß, Josefine Schardey, Stefan Schopf, Hans-Martin Schardey, Ulrich Wirth
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: BMC Surgery, Vol 23, Iss 1, Pp 1-7 (2023)
Druh dokumentu: article
ISSN: 1471-2482
DOI: 10.1186/s12893-023-02172-7
Popis: Abstract Purposes Postoperative bleeding remains a life-threatening complication in thyroid surgery. The aim was to assess the efficacy of four different hemostatic agents, Collagen-Fibrinogen-Thrombin Patch (CFTP) in two sizes (3 × 2.5 cm and 9.5 × 4.8 cm), polysaccharide particles (1 g) and Cellulose Gauze (2.5 × 5 cm) on postoperative drainage volume (DV) compared to a control group. Methods We included from October 2007 until Mai 2011, 150 patients (30 per group) for this monocentric, retrospective case-controlled study. Patients were scheduled for a hemithyroidectomy or thyroidectomy. The primary endpoint was the postoperative DV within the first 24 h, secondary the incidence of adverse events. Results There were no difference in demographic parameters. The mean DV (± SD) was 51.15 (± 36.86) ml in the control, 50.65 (± 42.79) ml in small (3 × 2.5 cm), 25.38 (± 23.99) ml in large CFTP (9.5 × 4.8 cm), 53.11 (± 39.48) ml in the polysaccharide particles and 48.94 (± 30.59) ml in the cellulose gauze group. DV was significantly reduced with the large CFTP (p
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