An Efficient Green Procedure for Synthesis of Some Fluorinated Curcumin Analogues Catalyzed by Calcium Oxide under Microwave Irradiation and Its Antibacterial Evaluation
| Autor: | S. Elavarasan, D. Bhakiaraj, T. Elavarasan, M. Gopalakrishnan |
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| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: | |
| Zdroj: | Journal of Chemistry, Vol 2013 (2013) |
| Druh dokumentu: | article |
| ISSN: | 2090-9063 2090-9071 |
| DOI: | 10.1155/2013/640936 |
| Popis: | A series of fluorine substituted curcumin analogues have been synthesized in a cheaper and greener method using calcium oxide as catalyst under microwave irradiation. All the synthesized compounds have been characterized by FT-IR, MS, elemental analysis, and 1H and 13C NMR spectroscopic techniques and screened for antibacterial activities against Staphylococcus aureus, β-Heamolytic streptococcus, Shigella flexneri, Vibrio cholerae, Pseudomonas aeruginosa, and Klebsiella pneumonia. All the synthesized compounds are showing good zone of inhibition against the tested bacterial strains. |
| Databáze: | Directory of Open Access Journals |
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