Autor: |
Yong Kyun Kim, Kil-Byung Lim, Sang Chul Lee, Jin-Woo Park, Hong-Jae Lee, Bum Sun Kwon, Ho Jun Lee |
Jazyk: |
angličtina |
Rok vydání: |
2014 |
Předmět: |
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Zdroj: |
Dementia and Geriatric Cognitive Disorders Extra, Vol 4, Iss 3, Pp 395-401 (2014) |
Druh dokumentu: |
article |
ISSN: |
1664-5464 |
DOI: |
10.1159/000363622 |
Popis: |
Background/Aims: In dementia patients, a deficit in activities of daily living (ADL) is one of the main problems. Our objective was to assess ADL using the Korean Modified Barthel Index (K-MBI) in patients with Alzheimer's disease (AD) plus cerebrovascular disease (CVD) treated with a rivastigmine patch for 24 weeks in an open-label, observational study. Methods: 29 patients were enrolled who met the National Institute of Neurological and Communicative Disorders and Stroke/Alzheimer's Disease and Related Disorders Association (NINCDS/ ANDRA) criteria and had a score of 10-26 on the Korean version of the Mini-Mental State Examination (K-MMSE). After the rivastigmine patch had been applied for 24 weeks, changes in self-care activities were assessed using the K-MBI. Results: The average age of the patients was 62.8 years, and they had an average K-MMSE score of 16.2. Patients showed a mean improvement of 21.9 points, as compared with the baseline K-MBI score of 30.3 (p Conclusion: In this multicenter, open-label, observational study, the rivastigmine patch was associated with improvements in ADL in patients with AD plus CVD. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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