Exemestane in the prevention setting

Autor: Jennifer Keating Litton, Therese B. Bevers, Banu K. Arun
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Zdroj: Therapeutic Advances in Medical Oncology, Vol 4 (2012)
Druh dokumentu: article
ISSN: 1758-8340
1758-8359
17588340
DOI: 10.1177/1758834012438214
Popis: Aromatase inhibitors are well-established therapies in the neoadjuvant, adjuvant and metastatic settings for breast cancer. In adjuvant trials, this class of drugs has shown preventative properties by decreasing the rate of contralateral breast cancer. Recently, the National Cancer Institute of Canada Clinical Trials Group MAP.3 study evaluated exemestane as a breast cancer prevention agent for women with specified higher risks of developing breast cancer. We review the history of exemestane and evaluate the available evidence of its use for breast cancer prevention.
Databáze: Directory of Open Access Journals