Exemestane in the prevention setting
Autor: | Jennifer Keating Litton, Therese B. Bevers, Banu K. Arun |
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Jazyk: | angličtina |
Rok vydání: | 2012 |
Předmět: | |
Zdroj: | Therapeutic Advances in Medical Oncology, Vol 4 (2012) |
Druh dokumentu: | article |
ISSN: | 1758-8340 1758-8359 17588340 |
DOI: | 10.1177/1758834012438214 |
Popis: | Aromatase inhibitors are well-established therapies in the neoadjuvant, adjuvant and metastatic settings for breast cancer. In adjuvant trials, this class of drugs has shown preventative properties by decreasing the rate of contralateral breast cancer. Recently, the National Cancer Institute of Canada Clinical Trials Group MAP.3 study evaluated exemestane as a breast cancer prevention agent for women with specified higher risks of developing breast cancer. We review the history of exemestane and evaluate the available evidence of its use for breast cancer prevention. |
Databáze: | Directory of Open Access Journals |
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