Autor: |
Musa Toyin Yakubu, Rukayat Oluwatoyin Jimoh |
Jazyk: |
angličtina |
Rok vydání: |
2015 |
Předmět: |
|
Zdroj: |
Middle East Fertility Society Journal, Vol 20, Iss 3, Pp 192-197 (2015) |
Druh dokumentu: |
article |
ISSN: |
1110-5690 |
DOI: |
10.1016/j.mefs.2014.10.001 |
Popis: |
Study objective: This study aimed to investigate the effects of aqueous extract of Carpolobia lutea root on the androgenic indices of paroxetine-treated male rats. Materials and methods: Sexually active, male rats (133.10 ± 4.21 g) were completely randomized into five groups (A–E) of 5 animals each. Rats in group A received 0.5 ml of distilled water once daily for 7 days while those in groups B, C, D and E which were induced with anti-androgenicity (oral administration of 10 mg/kg of paroxetine suspension, once daily for 21 days) received 0.5 ml of distilled water and 0.5 ml corresponding to 47, 94 and 141 mg/kg body weight of the extract respectively. Outcome: Administration of paroxetine significantly (p |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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