Radiopharmaceuticals: From Molecular Imaging to Targeted Radionuclide Therapy
| Autor: | P. August Schubiger, Jürgen Grünberg, Simon Mensah Ametamey, Michael Honer, Elisa Garcia-Garayoa, Peter Bläuenstein, Robert Waibel, Ilse Novak-Hofer, Roger Schibli |
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| Jazyk: | German<br />English<br />French |
| Rok vydání: | 2004 |
| Předmět: | |
| Zdroj: | CHIMIA, Vol 58, Iss 10 (2004) |
| Druh dokumentu: | article |
| ISSN: | 0009-4293 2673-2424 |
| DOI: | 10.2533/000942904777677489 |
| Popis: | The research and development of smart radiodrugs is the goal of the Center of Radiopharmaceutical Science of ETH, PSI, and USZ. Positron Emission Tomography (PET) allows the non-invasive visualization of biochemical processes within the body. Radiolabeled PET-tracers allow the study of neurophysiological diseases like Alzheimer, Parkinson's disease or the imaging of metastatic tumors. PET-techniques are nowadays an important part of routine nuclear medicine diagnosis. Tumor-cell targeting biomolecules (e.g. antibodies or peptides) coupled to therapeutic radionuclides can sterilize the malignant cells while sparing healthy tissue. This so-called targeted radionuclide therapy has made tremendous progress in the recent years and the first approved radiotherapeutics are available for clinical use. |
| Databáze: | Directory of Open Access Journals |
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