Using somatic variant richness to mine signals from rare variants in the cancer genome

Autor: Saptarshi Chakraborty, Arshi Arora, Colin B. Begg, Ronglai Shen
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-019-13402-z
Popis: Sequencing cancer genomes reveals low frequency novel somatic variants without known function. Here, the authors leverage statistical methodology from the fields of computational linguistics and ecology to highlight the potentially important signals harboured by these novel variants that are often dismissed.
Databáze: Directory of Open Access Journals