Phenolic derivatives and other chemical compounds from Cochlospermum regium

Autor: Soraya Solon, Carlos Alexandre Carollo, Luiz Fabrício Gardini Brandão, Cristiana dos Santos de Macedo, André Klein, Carlos Alan Dias-Junior, João Máximo de Siqueira
Jazyk: English<br />Spanish; Castilian<br />Portuguese
Rok vydání: 2012
Předmět:
Cochlospermum
antimicrobial activity
dihydrokaempferol-3-O-β-(6"-galloyl)-glucopyranoside
Chemistry
QD1-999
Zdroj: Química Nova, Vol 35, Iss 6, Pp 1169-1172 (2012)
Druh dokumentu: article
ISSN: 1678-7064
0100-4042
DOI: 10.1590/S0100-40422012000600019
Popis: This study describes the chemical investigation of the ethyl acetate fraction obtained from the hydroethanolic extract of the xylopodium of Cochlospermum regium (Mart. & Schr.) Pilger, which has been associated with antimicrobial activity. Phytochemical investigation produced seven phenol derivatives: ellagic acid, gallic acid, dihydrokaempferol, dihydrokaempferol-3-O-β-glucopyranoside, dihydrokaempferol-3-O-β-(6"-galloyl)-glucopyranoside, pinoresinol, and excelsin. It also contained two triacylbenzenes, known as cochlospermines A and B. The hydroethanolic extract and its fractions exhibited antimicrobial activity (0.1 mg/mL) against Staphylococcus aureus and Pseudomonas aeruginosa. Gallic acid showed activity against S. aureus. Dihydrokaempferol-3-O-β-(6"-galloyl)-glucopyranoside is reported here for the first time in the literature.
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