Tetraspanin 4 stabilizes membrane swellings and facilitates their maturation into migrasomes

Autor: Raviv Dharan, Yuwei Huang, Sudheer Kumar Cheppali, Shahar Goren, Petr Shendrik, Weisi Wang, Jiamei Qiao, Michael M. Kozlov, Li Yu, Raya Sorkin
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Nature Communications, Vol 14, Iss 1, Pp 1-9 (2023)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-023-36596-9
Popis: Migrasomes are signaling organelles that form in retraction fibers of migrating cells. Here authors show that migrasomes form by a two-stage process: an initial local membrane swelling matures and is stabilized by recruited tetraspanin proteins.
Databáze: Directory of Open Access Journals
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