Experience in using intravenous thrombolysis in ischemic stroke in Tatarstan
| Autor: | D. R. Khasanova, T. V. Demin |
|---|---|
| Jazyk: | ruština |
| Rok vydání: | 2011 |
| Předmět: | |
| Zdroj: | Неврология, нейропсихиатрия, психосоматика, Vol 3, Iss 1, Pp 42-46 (2011) |
| Druh dokumentu: | article |
| ISSN: | 2074-2711 2310-1342 |
| DOI: | 10.14412/2074-2711-2011-133 |
| Popis: | The paper describes experience with intravenous thrombolysis used in a few vascular centers of the Republic of Tatarstan in the past 5 years. Intravenous thrombolysis with alteplase (actilise) was carried in 300 patients (188 men and 112 women) aged 21 to 79 years (mean age 59.8±13.7 years) who had ischemic stroke (IS). Significant positive changes (a neurological deficit decrease on the NIHSS score by ≥ 4 points) were observed in 67.3% of cases; mortality was 6.7%. Hemorrhagic events as asymptomatic hemorrhagic transformations were found in 19.3% of cases with the neurological disorders being progressive in 4.6%. Recanalization of internal carotid artery occlusion was recorded only in 24.0% of the patients and that of occlusion of the proximal segments of the middle cerebral artery was in 50.1%. Examples of effective intravenous thrombolysis in IS in the carotid and vertebrobasilar beds are given. Whether intravenous thrombolysis can be more extensively used in IS is discussed. |
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