Catheter‐Based Renal Denervation for Resistant Arterial Hypertension: 10‐Year Real‐World Follow‐Up Data

Autor: Sofie Brouwers, Giulia Botti, Matthias Verbesselt, Lucio Addeo, Marta Belmonte, Kostas Bermpeis, Dario Tino Bertolone, Chiara Valeriano, Michele Mattia Viscusi, Eric Wyffels
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: The Journal of Clinical Hypertension, Vol 26, Iss 12, Pp 1521-1527 (2024)
Druh dokumentu: article
ISSN: 1751-7176
1524-6175
DOI: 10.1111/jch.14931
Popis: ABSTRACT This analysis of real‐world data examines the efficacy, safety, and long‐term outcomes of renal denervation in hypertensive patients for up to 10 years. Sixty‐five consecutive patients underwent renal denervation (RDN) (single operator) for uncontrolled resistant hypertension. Efficacy was defined as the interindividual change of office (OBPM) and ambulatory blood pressure monitoring (ABPM) at 1, 6, 12 months, 2–4 and 5–10 years after RDN. Medication changes, renal function, and device generation disparities were analyzed. Of these patients, 42 received RDN with a first‐generation device, while 23 underwent the procedure with a second‐generation device. Baseline demographics included a predominantly male cohort (57.6%) with an average age of 60.3 years. The mean number of medications at baseline was 4.3. OBPM at baseline was 169.0/87.4 mmHg, and ABPM at baseline was 153.4/88.4 mmHg. Post‐procedure, significant reductions in systolic blood pressure (SBP) were observed in both OBPM and ABPM at 1 month (OBPM 147.9/82.8 mmHg; ABPM 141.3/83.0 mmHg [SBP, p
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