Autor: |
Christian Eseigbe Imafidon, Rufus Ojo Akomolafe, Omotayo Alaba Eluwole, Isiaka Ayofe Adekunle, Ruby Adebusola Agbaje |
Jazyk: |
angličtina |
Rok vydání: |
2019 |
Předmět: |
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Zdroj: |
Clinical Phytoscience, Vol 5, Iss 1, Pp 1-13 (2019) |
Druh dokumentu: |
article |
ISSN: |
2199-1197 |
DOI: |
10.1186/s40816-019-0118-y |
Popis: |
Abstract Background Lead (Pb) remains an apparently indispensable material in several industrial processes. It is a potent environmental toxin with associated deleterious biological effects. The study investigated the effects of aqueous garlic extract (AGE) on renal clearance and proteinuria in Wistar rats with Pb-induced kidney injury. Methods Thirty male Wistar rats were divided into six groups of five rats each such that exposure to Pb (35 mg/kg i.p) for 10 consecutive days was either followed by 30 days recovery period (without treatment) or 30 days post-treatment with oral graded doses of AGE at 100, 200 and 400 mg/kg while comparisons where made against a control (2 ml/kg NORMAL SALINE) at p |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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