Open Radical Cystectomy: Single Center Results and Outcomes in the Last Five Years

Autor: Bojan Čikić, Toni Zekulić, Luka Penezić, Jerko Anđelić, Tomislav Kuliš, Hrvoje Saić, Ahmad El-Saleh, Vedran Andrijašević, Tvrtko Hudolin, Eleonora Goluža, Željko Kaštelan
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Acta Clinica Croatica, Vol 62., Iss Supplement 2, Pp 21-27 (2023)
Druh dokumentu: article
ISSN: 0353-9466
1333-9451
DOI: 10.20471/acc.2023.62.s2.3
Popis: Radical cystectomy is a therapeutic modality of choice for many patients with muscle- invasive bladder cancer. We conducted a retrospective study of open radical cystectomies performed at a single Center from January 2017 to January 2022. Decision on the urinary diversion type was based on tumor stage, comorbidities, patient age, general condition and preferences. There were 19.5% of female and 80.5% of male patients, median age 67 (range 38-90) years. We performed 96 (44.7%) ureterocutaneostomies (UCS), 67 (31.2%) ileal conduit derivations, and 52 (24.2%) orthotopic neobladder derivations (OND). There were 17 (7.9%) complications after UCS, 7 (3.2%) after incontinent urinary diversion, and 7 (3.2%) after OND. Fifty-five (25.6%) patients developed early complications, of which 31 (14.4%) during the initial hospitalization period, and 24 (11.2%) required re-hospitalization in the 30-day postoperative period. The most common wound-related complication was wound dehiscence, most typically caused by infection. The main reason for readmission was urosepsis. The 30-day mortality rate was 0.9%. Late complications that occurred 30 days after the operation were found in 39 (18.1%) cases. Bladder cancer is a high-mortality disease that requires a multidisciplinary and personalized approach. Further development of multidisciplinary teams, perioperative and postoperative care, and follow- up strategy is needed to improve the oncologic and functional outcomes of this procedure.
Databáze: Directory of Open Access Journals
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