Comparison between Intramuscular and Intranasal Administration of Sedative Drugs Used for Piglet Castration

Autor: Andreas Breitenlechner, Moritz Bünger, Ursula Katharina Ruczizka, Marlies Dolezal, Ulrike Auer, Andrea Buzanich-Ladinig
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Animals, Vol 14, Iss 16, p 2325 (2024)
Druh dokumentu: article
ISSN: 2076-2615
DOI: 10.3390/ani14162325
Popis: The aim of this study was to test the intranasal administration of different anaesthetics in piglets less than seven days of age undergoing castration for their suitability for providing good-quality sedation and short induction and recovery time with minimal stress. Azaperone alone at a high (5 mg/kg), medium (3 mg/kg) and low dosage (2 mg/kg) and in two combinations with either alfaxalone or midazolam were applied intramuscularly (i.m.) or intranasally (i.n.) to 120 healthy piglets. Compared to intramuscular application, intranasal application showed longer induction times, shorter recovery times and higher scores for defence and vocalisation. In conclusion, the intranasal protocols did not meet the requirements in all groups and their use can therefore not be recommended. A rapid induction phase and good quality of sedation could not be guaranteed.
Databáze: Directory of Open Access Journals
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