Asymmetric Synthesis of 1,3-Oxazolidine Derivatives with Multi-Component Reaction and Research of Kinetic Resolution

Autor: Xiao-Wei Hong, Yu-Qiang Zhou, Cui-Bing Bai, Nai-Xing Wang, Yalan Xing, Wei Zhang, Yan-Jing Wang, Xing-Wang Lan, Yu Xie, Yi-He Li
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Molecules, Vol 20, Iss 9, Pp 17208-17220 (2015)
Druh dokumentu: article
ISSN: 1420-3049
DOI: 10.3390/molecules200917208
Popis: An efficient multi-component reaction to synthesize multi-substituted 1,3-oxazolidine compounds of high optical purity was described. All the products were well-characterized and the absolute configuration of one chiral center was determined. The plausible mechanism was proposed and a kinetic resolution of epoxides process was confirmed.
Databáze: Directory of Open Access Journals