Metabolic Profile of People Living with HIV in a Treatment Hub in Manila, Philippines
| Autor: | Christian Francisco, Eddieson Gonzales, Marc Gregory Yu, Edsel Maurice Salvaña, Cybele Abad, Paul Ferdinand Reganit, Patricia Maningat, Olivia Sison, Marissa Alejandria |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Journal of the ASEAN Federation of Endocrine Societies, Vol 37, Iss 1 (2022) |
| Druh dokumentu: | article |
| ISSN: | 0857-1074 2308-118X |
| DOI: | 10.15605/jafes.037.01.17 |
| Popis: | Objectives. People living with HIV (PLHIV) are susceptible to develop dyslipidemia and hyperglycemia. This study aims to determine the prevalence of these metabolic derangements among Filipino PLHIV. Methodology. We reviewed 635 medical records in a treatment hub in Manila, Philippines from January 2004 to July 2016. Logistic regression analysis was done to determine factors associated with dyslipidemia and hyperglycemia pre- and post-ART. Results. Among 635 PLHIV, 97.3% were males with mean age of 30 years and median CD4 count of 207 cells/mm3. Pre-ART, prevalence of dyslipidemia was 65.4% and hyperglycemia was 10.4%. Risk factors for dyslipidemia include hyperglycemia (AOR 3.8, p 0.001) and >320 days delay in ART initiation from HIV confirmation (AOR 1.5, p 0.032), while dyslipidemia was associated with hyperglycemia (AOR 3.1, p 0.001). Post-ART, prevalence of dyslipidemia was 48.6% and hyperglycemia was 15.6%. Risk factors for post-ART dyslipidemia include being WHO stage 4 (AOR 2.1, p 0.021), hyperglycemia (AOR 16.1, p36 months ART duration (AOR 8.7, p30 years (AOR 2.1, p 0.004), being overweight (AOR 1.8, p 0.023), dyslipidemia (AOR 17.8, p |
| Databáze: | Directory of Open Access Journals |
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