Brazilian Protocol for Sexually Transmitted Infections 2020: syphilis diagnostic tests

Autor: Pâmela Cristina Gaspar, Álisson Bigolin, José Boullosa Alonso Neto, Esdras Daniel dos Santos Pereira, Maria Luiza Bazzo
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Revista da Sociedade Brasileira de Medicina Tropical, Vol 54, Iss suppl 1 (2021)
Druh dokumentu: article
ISSN: 1678-9849
0037-8682
DOI: 10.1590/0037-8682-630-2020
Popis: Abstract The recommendations for diagnostic tests for investigating syphilis are part of the Clinical Protocol and Therapeutic Guidelines for Comprehensive Care for People with Sexually Transmitted Infections and the Technical Manual for Syphilis Diagnosis, published by the Brazilian Ministry of Health. These recommendations were developed based on scientific evidence and discussions with a panel of experts. This article presents direct tests to detect Treponema pallidum in lesions and algorithms that combine treponemal and non-treponemal antibody tests to assist in syphilis diagnosis, with the aim of contributing to the efforts of health service managers and health professionals in qualifying health care. The article also covers the use of non-treponemal tests to investigate neurosyphilis and guidelines for interpreting non-treponemal antibody titers in monitoring the treatment and diagnosis of congenital syphilis, as well as prospects for innovations in diagnosis. The critical role of rapid immunochromatographic treponemal tests for public health and for addressing syphilis is also highlighted.
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