The effect and safety of periarticular multimodal drug injection without morphine and epinephrine in anterior cruciate ligament reconstruction
| Autor: | Changhun Han, Yusuke Hashimoto, Sunao Nakagawa, Shinji Takahashi, Yohei Nishida, Shinya Yamasaki, Junsei Takigami, Hiroaki Nakamura |
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| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Journal of Orthopaedics, Trauma and Rehabilitation, Vol 30 (2023) |
| Druh dokumentu: | article |
| ISSN: | 2210-4925 22104917 |
| DOI: | 10.1177/22104917221136285 |
| Popis: | Background Periarticular multimodal drug injection (PMDI) is a safe and effective pain management technique after anterior cruciate ligament reconstruction (ACLR); however, adding morphine and epinephrine sometimes causes adverse effects. Therefore, we evaluated the efficacy of PMDI without morphine and epinephrine after ACLR. Methods This retrospective matched case-control study included patients who had undergone primary double-bundle ACLR with PMDI and were then matched one-to-one with a control group without PMDI based on sex, age, and body mass index using propensity-matched analysis. The following clinical outcomes were compared between the groups: visual analog scale (VAS) score, C-reactive protein (CRP) concentration, number of times the patients used additional analgesics, complication rate, and postoperative time to achieve straight leg raise (SLR). Results Twenty-nine patients with PMDI and 29 controls were enrolled. The VAS score at 1 day postoperatively was lower in the PMDI than the control group (1.93 ± 1.44 vs. 3.41 ± 1.75, respectively; P |
| Databáze: | Directory of Open Access Journals |
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