Factors Associated with Prolonged RT-PCR SARS-CoV-2 Positive Testing in Patients with Mild and Moderate Forms of COVID-19: A Retrospective Study
| Autor: | Nicoleta Stefania Motoc, Victoria-Maria Ruta, Milena Adina Man, Rodica Ana Ungur, Viorela Mihaela Ciortea, Laszlo Irsay, Andrea Nicola, Dan Valean, Lia Oxana Usatiuc, Ileana Rodica Matei, Ileana Monica Borda |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Medicina, Vol 58, Iss 6, p 707 (2022) |
| Druh dokumentu: | article |
| ISSN: | 58060707 1648-9144 1010-660X |
| DOI: | 10.3390/medicina58060707 |
| Popis: | Background and objectives: This article aims to evaluate the number of days necessary for patients with mild and moderate forms of COVID-19 to reach undetectable levels of SARS-CoV-2 RNA in the upper respiratory tract specimens. As a secondary objective, we sought to establish a correlation between different conditions associated with longer viral load as this could result in a longer period of contagion and infectivity. Materials and Methods: It is a retrospective study. A total of 70 patients with confirmed mild and moderate forms of COVID-19 were enrolled in our study. Results: Number of days with traceable viral load was 25.93 (±6.02) days in patients with mild COVID-19 and 26.97 (±8.30) in moderate form (p = 0.72). Age, male gender, and obesity, along with several chronic conditions (cardiac, liver, renal, and neurological disease), were associated with prolonged positive RT-PCR test from the nasal swab (therefore prolonged viral load). These are in general, risk factors for severe forms of COVID-19. Conclusions: There are several conditions associated with prolonged positive RT-PCR in mild and moderate forms of COVID-19. As to why and what is the significance of it remains to be studied. |
| Databáze: | Directory of Open Access Journals |
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