Flupirtine : Clinical pharmacology

Autor: S Harish, K Bhuvana, Girish M Bengalorkar, T N Kumar
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Zdroj: Journal of Anaesthesiology Clinical Pharmacology, Vol 28, Iss 2, Pp 172-177 (2012)
Druh dokumentu: article
ISSN: 0970-9185
DOI: 10.4103/0970-9185.94833
Popis: Flupirtine is neither an opioid nor a non steroidal anti-inflammatory drug (NSAID) producing its analgesic action through blockade of glutamate N-methyl-D-aspartate receptor. It is devoid of adverse effects of routinely used analgesic drugs, but is equally efficacious in reducing pain sensation. It has a distinctive mechanism of action, exerting a dual therapeutic effect with both analgesic and muscle relaxant properties that has utility in the treatment of pain, including that associated with muscle tension.
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