Design Approaches and Computational Tools for DNA Nanostructures

Autor: Heeyuen Koh, Jae Gyung Lee, Jae Young Lee, Ryan Kim, Osamu Tabata, Jin-Woo Kim, DO-Nyun Kim
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: IEEE Open Journal of Nanotechnology, Vol 2, Pp 86-100 (2021)
Druh dokumentu: article
ISSN: 2644-1292
DOI: 10.1109/OJNANO.2021.3119913
Popis: Designing a structure in nanoscale with desired shape and properties has been enabled by structural DNA nanotechnology. Design strategies in this research field have evolved to interpret various aspects of increasingly more complex nanoscale assembly and to realize molecular-level functionality by exploring static to dynamic characteristics of the target structure. Computational tools have naturally been of significant interest as they are essential to achieve a fine control over both shape and physicochemical properties of the structure. Here, we review the basic design principles of structural DNA nanotechnology together with its computational analysis and design tools.
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