An acute hemolytic transfusion reaction due to the 'anti-c' rhesus antibody: A case report emphasizing the role of transfusion medicine

Autor:	Deepti Sachan, Rajeswari Jayakumar, Joy Varghese, Mohamed Rela
Jazyk:	angličtina
Rok vydání:	2015
Předmět:	Antibody hemolytic rhesus transfusion transfusion reaction Diseases of the blood and blood-forming organs RC633-647.5
Zdroj:	Asian Journal of Transfusion Science, Vol 9, Iss 2, Pp 213-215 (2015)
Druh dokumentu:	article
ISSN:	0973-6247 1998-3565
DOI:	10.4103/0973-6247.154256
Popis:	Rhesus (Rh) mediated hemolytic transfusion reactions (HTR) are usually immunoglobulin G mediated and delayed onset. Rh antibodies being the cause of acute HTR (AHTR) and intravascular hemolysis are still under debate. We report here a case of a 53-year-old male who developed AHTR due to "anti-c" antibodies within 3 h of blood transfusion, precipitating fatal acute liver failure in a patient with hepatitis C related chronic liver disease. This case emphasizes the need of inclusion of antibody screening in routine pretransfusion testing as well as a critical role of transfusion medicine specialists for early diagnosis and minimizing transfusion-related morbidity and mortality.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/2ad10b9414c148d5ba0e8e863de0ad97 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF