An acute hemolytic transfusion reaction due to the 'anti-c' rhesus antibody: A case report emphasizing the role of transfusion medicine
Autor: | Deepti Sachan, Rajeswari Jayakumar, Joy Varghese, Mohamed Rela |
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Jazyk: | angličtina |
Rok vydání: | 2015 |
Předmět: | |
Zdroj: | Asian Journal of Transfusion Science, Vol 9, Iss 2, Pp 213-215 (2015) |
Druh dokumentu: | article |
ISSN: | 0973-6247 1998-3565 |
DOI: | 10.4103/0973-6247.154256 |
Popis: | Rhesus (Rh) mediated hemolytic transfusion reactions (HTR) are usually immunoglobulin G mediated and delayed onset. Rh antibodies being the cause of acute HTR (AHTR) and intravascular hemolysis are still under debate. We report here a case of a 53-year-old male who developed AHTR due to "anti-c" antibodies within 3 h of blood transfusion, precipitating fatal acute liver failure in a patient with hepatitis C related chronic liver disease. This case emphasizes the need of inclusion of antibody screening in routine pretransfusion testing as well as a critical role of transfusion medicine specialists for early diagnosis and minimizing transfusion-related morbidity and mortality. |
Databáze: | Directory of Open Access Journals |
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