| Autor: |
William S. Chen, Ranjit S. Bindra, Allen Mo, Thomas Hayman, Zain Husain, Joseph N. Contessa, Stephen G. Gaffney, Jeffrey P. Townsend, James B. Yu |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| Předmět: |
|
| Zdroj: |
Frontiers in Oncology, Vol 8 (2018) |
| Druh dokumentu: |
article |
| ISSN: |
2234-943X |
| DOI: |
10.3389/fonc.2018.00095 |
| Popis: |
BackgroundHPV infection is associated with high p16 expression and good prognosis in head and neck squamous cell carcinomas (HNSCCs). Analysis of CDKN2A, the gene encoding p16, may further elucidate the association between p16 expression and prognosis. We sought to determine whether CDKN2A copy number loss was associated with poor survival in HPV-negative HNSCCs.MethodsThe Cancer Genome Atlas HNSCC clinical and genomic data were obtained and integrated. Patients |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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