| Autor: |
Jie Li, Phillip M. Galbo, Weida Gong, Aaron J. Storey, Yi-Hsuan Tsai, Xufen Yu, Jeong Hyun Ahn, Yiran Guo, Samuel G. Mackintosh, Ricky D. Edmondson, Stephanie D. Byrum, Jason E. Farrar, Shenghui He, Ling Cai, Jian Jin, Alan J. Tackett, Deyou Zheng, Gang Greg Wang |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-021-21357-3 |
| Popis: |
The fusion gene ZMYND11-MBTD1 (ZM) is present in a subgroup of patients with acute myeloid leukaemia (AML). Here, the authors show that ZM expression induces AML in a murine model though activating the NuA4/TIP60 histone acetyltransferase complex. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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