Autor: |
Teruhiko Imamura, Nikhil Narang, Gene Kim, Jayant Raikhelkar, Ben Chung, Ann Nguyen, Luise Holzhauser, Daniel Rodgers, Sara Kalantari, Bryan Smith, Takeyoshi Ota, Tae Song, Colleen Juricek, Daniel Burkhoff, Valluvan Jeevanandam, Gabriel Sayer, Nir Uriel |
Jazyk: |
angličtina |
Rok vydání: |
2020 |
Předmět: |
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Zdroj: |
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 7 (2020) |
Druh dokumentu: |
article |
ISSN: |
2047-9980 |
DOI: |
10.1161/JAHA.119.014801 |
Popis: |
Background Decoupling between diastolic pulmonary artery pressure and pulmonary capillary wedge pressure is an index of pulmonary vascular damage. This study assessed the impact of decoupling on right heart function and hemocompatibility‐related adverse events. Methods and Results In this prospective study, patients underwent invasive hemodynamic tests following left ventricular assist device implantation. Decoupling was defined as a difference of >5 mm Hg between diastolic pulmonary artery pressure and pulmonary capillary wedge pressure. Among 92 patients with left ventricular assist devices (median age, 61 years; 57% male), 44 patients (48%) had decoupling. Right heart function and size by echocardiographic assessment worsened during a 1‐year observational period in the decoupling group as compared with the control group (P |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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