Effects of Hibiscus sabdariffa Linn. fruit extracts on α-glucosidase enzyme, glucose diffusion and wound healing activities

Autor: Raheem Mohssin Shadhan, Siti Pauliena Mohd Bohari
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Asian Pacific Journal of Tropical Biomedicine, Vol 7, Iss 5, Pp 466-472 (2017)
Druh dokumentu: article
ISSN: 2221-1691
DOI: 10.1016/j.apjtb.2017.01.023
Popis: Objective: To provide in vitro evidence for antidiabetic activity through potential inhibition of α-glucosidase enzyme, glucose diffusion and enhancement in the wound healing using methanolic extract and fractions from Hibiscus sabdariffa Linn. fruit. Methods: The inhibitory action of methanolic extract and fractions of such fruit on α-glucosidase enzyme and glucose movement through in vitro assay assessment was reported. Their activities on wound healing were tested using the scratch assay. Results: Ethyl acetate fraction at 50 mg/mL concentration exhibited significant α-glucosidase inhibition (95.79 mg/mL) with P
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