Joint analysis of expression levels and histological images identifies genes associated with tissue morphology

Autor: Jordan T. Ash, Gregory Darnell, Daniel Munro, Barbara E. Engelhardt
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Druh dokumentu: article
ISSN: 2041-1723
97061786
DOI: 10.1038/s41467-021-21727-x
Popis: Image features from histological slides can be used as informative endophenotypes in association studies for tissue-localized pathologies. Here, the authors develop ImageCCA, a framework for joint analysis of paired gene expression and histology data derived from automatically extracted image features.
Databáze: Directory of Open Access Journals
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