Preservation of the celiac branch of the vagus nerve reduces the incidence of postoperative diarrhea in gastric cancer: a cohort study

Autor: Hao Guo, WeiFeng Sun, HaiTao Duan, Chi Zhang, MaoHua Wei, Pin Liang, Xiang Hu, Liang Cao
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: World Journal of Surgical Oncology, Vol 22, Iss 1, Pp 1-12 (2024)
Druh dokumentu: article
ISSN: 1477-7819
DOI: 10.1186/s12957-024-03370-0
Popis: Abstract Background To investigate the short-term and long-term outcomes of preserving the celiac branch of the vagus nerve during laparoscopic distal gastrectomy. Methods A total of 149 patients with prospective diagnosis of gastric cancer who underwent laparoscopic-assisted distal gastrectomy (LADG) combined with Billroth-II anastomosis and D2 lymph node dissection between 2017 and 2018 were retrospectively analyzed. The patients were divided into the preserved LADG group (P-LADG, n = 56) and the resected LADG group (R-LADG, n = 93) according to whether the vagus nerve celiac branch was preserved. We selected 56 patients (P-LADG, n = 56) with preservation of the celiac branch of the vagus nerve and 56 patients (R-LADG, n = 56) with removal of the celiac branch of the vagus nerve by propensity-matched score method. Postoperative nutritional status, weight change, short-term and long-term postoperative complications, and gallstone formation were evaluated in both groups at 5 years of postoperative follow-up. The status of residual gastritis and bile reflux was assessed endoscopically at 12 months postoperatively. Results The incidence of diarrhea at 5 years postoperatively was lower in the P-LADG group than in the R-LADG group (p
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