Angiogenesis Inhibitors as Anti-Cancer Therapy Following Renal Transplantation: A Case Report and Review of the Literature

Autor:	Lawrence Kasherman, Jeffrey Doi, Katherine Karakasis, Jeffrey Schiff, Abhijat Kitchlu, Stephanie Lheureux, Amit M. Oza
Jazyk:	angličtina
Rok vydání:	2021
Předmět:	bevacizumab vascular endothelial growth factor angiogenesis inhibitor transplant proteinuria nephrotoxicity Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Zdroj:	Current Oncology, Vol 28, Iss 1, Pp 661-670 (2021)
Druh dokumentu:	article
ISSN:	1718-7729 1198-0052
DOI:	10.3390/curroncol28010064
Popis:	Solid organ transplant recipients on long-term immunosuppressive medication are at increased risk of developing malignancy, and treatment of advanced cancers with angiogenesis inhibitors in this context has not been widely studied. We present a case of recurrent high-grade serous ovarian carcinoma treated with paclitaxel and bevacizumab in the context of prior renal transplantation where the patient responded well to treatment with controlled toxicities, discussing the potential for increased rates of adverse events and drug interactions in this select population.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/cd2a6aa6e8f14cbca3e659ed04a60424 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF