Diffuse large B cell lymphoma coexistence with systemic mastocytosis

Autor: Sheng-Hsuan Chien, Yao-Chung Liu, Ying-Chung Hong, Ching-Fen Yang, Chun-Yu Liu, Tzeon-Jye Chiou, Cheng-Hwai Tzeng, Jin-Hwang Liu, Jyh-Pyng Gau
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Journal of Cancer Research and Practice, Vol 3, Iss 2, Pp 45-48 (2016)
Druh dokumentu: article
ISSN: 2311-3006
DOI: 10.1016/j.jcrpr.2015.09.001
Popis: Systemic mastocytosis is a rare disease and characterized by excessive mast cell accumulation in one or multiple organs. One subtype of systemic mastocytosis is systemic mastocytosis-associated clonal hematological non-mast cell lineage disease (SM-AHMND), which indicates concurrent evolution of two separate clonal entities, one consisting of mast cells and one as a second hematological as well as non-mast cell origin disease. When SM-AHMND is diagnosed, bone marrow examination is essential for the initial approach, because marrow is almost universally involved in adult mastocytosis and it facilitates detection of a second hematological neoplasm. Myeloid neoplasm is reported to be the most prevalent associated clonal hematological non-mast cell disease. Treatment strategy and outcome for SM-AHMND is dependent on hematological non-mast cell lineage disease. Herein, we have presented a case report of diffuse large B cell lymphoma coexisting with systemic mastocytosis where the patient underwent successful chemotherapy leading to extended survival duration.
Databáze: Directory of Open Access Journals