Risk Factors Associated With Drug-Related Side Effects in Children: A Scoping Review

Autor: Esmaeel Toni MSc, Haleh Ayatollahi PhD, Reza Abbaszadeh MD, Alireza Fotuhi Siahpirani PhD
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Global Pediatric Health, Vol 11 (2024)
Druh dokumentu: article
ISSN: 2333-794X
2333794X
DOI: 10.1177/2333794X241273171
Popis: Objective . Children’s vulnerability to drug-related side effects has been highlighted in several studies. However, there is no consensus on the risk factors associated with these side effects. This study aimed to investigate risk factors associated with drug-related side effects in children. Methods . This scoping review was conducted across multiple databases. The search strategy was created with a focus on drug-related side effects, as they are more predictable based on the pre-determined risk factors. Data were collected, and reported narratively. Results . The demographic, health, hospital, and drug-related risk factors may cause drug-related side effects in children. Among them, low age, sex, polypharmacy, length of hospitalization, and medications used for comorbidities may increase the risk. Conclusion . While most of the risk factors might be similar in adults and children, their impact might be different in these 2 groups. Therefore, future studies should identify more details about the impact of the risk factors in children.
Databáze: Directory of Open Access Journals