Antihypertensive deprescribing in frail long-term care residents (OptimizeBP): protocol for a prospective, randomised, open-label pragmatic trial

Autor: Dean T Eurich, Erik Youngson, Christina S Korownyk, Jeffrey A Bakal, Douglas Faulder, Scott R Garrison, Donna P Manca, Roni Y Kraut, Cheryl A Sadowski, Ana Vucenovic, Carina Lundby, Paul Kivi, Margaret Manville
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: BMJ Open, Vol 14, Iss 8 (2024)
Druh dokumentu: article
ISSN: 2044-6055
DOI: 10.1136/bmjopen-2024-084619
Popis: Introduction Although antihypertensive medication use is common among frail older adults, observational studies in this population suggest blood pressure (BP) lowering may convey limited benefit and perhaps even harm. This protocol describes an antihypertensive deprescribing trial in frail older adults powered for mortality and morbidity outcomes.Methods and analysis Design: Prospective, parallel, randomised, open-label pragmatic trial.Participants: Long-term care (LTC) residents ≥70 years of age, diagnosed with hypertension, with mean systolic BP
Databáze: Directory of Open Access Journals