The effect of combining different sampling tools on the performance of electromagnetic navigational bronchoscopy for the evaluation of peripheral lung lesions and factors associated with its diagnostic yield

Autor: Javier Flandes, Francisco B. Martinez-Muñiz, Juan José Cruz-Rueda, Francisco J. Soto, Adnan Majid, Eduardo Tuta-Quintero, Luis F. Giraldo-Cadavid
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: BMC Pulmonary Medicine, Vol 23, Iss 1, Pp 1-10 (2023)
Druh dokumentu: article
ISSN: 1471-2466
DOI: 10.1186/s12890-023-02711-1
Popis: Abstract Background We assessed the performance of Electromagnetic navigational bronchoscopy (ENB) as a standalone diagnostic technique and the performance of different sampling tools used during the procedure. Methods We recruited 160 consecutive patients who underwent ENB for peripheral lung lesions (PLL) at a tertiary care centre. The diagnostic performance of ENB and sampling tools was assessed using a logistic regression model and a ROC-curve in which the dependent variable was diagnostic success. A multivariate model was built to predict diagnostic success before performing ENB to select the best candidates for the procedure. Results Most patients with PLLs in the study were male (65%), with a mean age of 67.9 years. The yield was 66% when the most common techniques were used together as suction catheter + transbronchial biopsy forceps (TBBx) + bronchoalveolar lavage + bronchial washing (p
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