SPYing on triplet repeat expansions: Insights into FAN1-MLH1 interaction and regulation

Autor: Robert S. Lahue
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Cell Reports, Vol 36, Iss 11, Pp 109736- (2021)
Druh dokumentu: article
ISSN: 2211-1247
DOI: 10.1016/j.celrep.2021.109736
Popis: Summary: The DNA repair proteins FAN1 and MLH1 have opposing effects on triplet repeat expansions. New studies by Goold et al. (2021) and Porro et al. (2021) pinpoint interactions between FAN1 and MLH1 that cross-regulate each other’s activities.
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