Unsuccessful transscleral cyclophotocoagulation in oculocutaneous albinism

Autor: Aaron D. Dotson, John H. Fingert, Erin A. Boese
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: American Journal of Ophthalmology Case Reports, Vol 34, Iss , Pp 102020- (2024)
Druh dokumentu: article
ISSN: 2451-9936
DOI: 10.1016/j.ajoc.2024.102020
Popis: Purpose: To report a case of unsuccessful transscleral cyclophotocoagulation in a patient with OCA1A tyrosinase-negative oculocutaneous albinism. Observations: A 35-year-old Asian female with molecularly diagnosed OCA1A (tyrosinase-negative) oculocutaneous albinism and unilateral severe mixed mechanism glaucoma underwent transscleral cyclophotocoagulation on two separate occasions to treat elevated intraocular pressure. The intraocular pressure remained markedly elevated approximately 1 month following two separate treatments of transscleral cyclophotocoagulation while using high energy settings. The poor efficacy of both cyclophotocoagulation treatments was most likely due to a lack of melanin in the setting of oculocutaneous albinism. Conclusions and importance: Cyclophotocoagulation in patients with oculocutaneous albinism is less likely to yield a desired lowering of intraocular pressure due to the absence of melanin.
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