Compensatory mechanisms in resistant Anopheles gambiae AcerKis and KdrKis neurons modulate insecticide-based mosquito control

Autor: Stéphane Perrier, Eléonore Moreau, Caroline Deshayes, Marine El-Adouzi, Delphine Goven, Fabrice Chandre, Bruno Lapied
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
Druh dokumentu: article
ISSN: 2399-3642
DOI: 10.1038/s42003-021-02192-0
Popis: Perrier et al. examine the neurons of mosquitoes following the development of insecticide resistance-associated point mutations in the voltage-gated sodium channels and AChE1 genes for two resistant strains, KdrKis and AcerKis. Their results show that nAChRs and the intracellular calcium concentration provide a compensatory mechanism for AcerKis and KdrKis neurons to insecticide exposure.
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