Pluripotency and X chromosome dynamics revealed in pig pre-gastrulating embryos by single cell analysis

Autor: Priscila Ramos-Ibeas, Fei Sang, Qifan Zhu, Walfred W. C. Tang, Sarah Withey, Doris Klisch, Liam Wood, Matt Loose, M. Azim Surani, Ramiro Alberio
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-019-08387-8
Popis: Lineage segregation from conception to gastrulation has been mapped at the single cell level in mouse, human and monkey. Here, the authors provide a comprehensive analysis of porcine preimplantation development using single cell RNA-seq; mapping metabolic changes, X chromosome inactivation and signalling pathways.
Databáze: Directory of Open Access Journals