Changes in intraocular pressure and horizontal pupil diameter during use of topical mydriatics in the canine eye

Autor: Liga Kovalcuka, Agris Ilgazs, Dace Bandere, David L. Williams
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Open Veterinary Journal, Vol 7, Iss 1, Pp 16-22 (2017)
Druh dokumentu: article
ISSN: 2218-6050
DOI: 10.4314/ovj.v7i1.3
Popis: The objective of this study was to determine the effects of topical 0.5% tropicamide, 1% atropine sulphate and 10% phenylephrine hydrochloride ophthalmic solutions on intraocular pressure (IOP) and horizontal pupil diameter (HPD) in the dog during the first hour after treatment. Forty clinically and ophthalmologically normal canine patients (between the ages of 2 and 6 years) of varying breed and sex were used in this study. Animals were randomly divided into four groups of ten and given one drop of tropicamide, atropine, phenylephrine or saline into one eye. IOP and HPD were measured in both eyes every 5 minutes for 60 minutes. Tropicamide increased IOP by 8.8±4.0 mmHg 35 minutes post-treatment compared to pre-treatment (P
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