Autor: |
Hector Salazar, Clarissa Eibl, Miriam Chebli, Andrew Plested |
Jazyk: |
angličtina |
Rok vydání: |
2017 |
Předmět: |
|
Zdroj: |
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017) |
Druh dokumentu: |
article |
ISSN: |
2041-1723 |
DOI: |
10.1038/ncomms14327 |
Popis: |
Partial agonists weakly activate receptors even when occupying all available binding sites. Here the authors show that partial agonists of the AMPA receptor drive the adoption of multiple inactive forms, accounting for their limited efficacy. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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