Genetic architecture of type 1 diabetes with low genetic risk score informed by 41 unreported loci

Autor: Hui-Qi Qu, Jingchun Qu, Jonathan Bradfield, Luc Marchand, Joseph Glessner, Xiao Chang, Michael March, Jin Li, John J. Connolly, Jeffrey D. Roizen, Patrick Sleiman, Constantin Polychronakos, Hakon Hakonarson
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Communications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
Druh dokumentu: article
ISSN: 2399-3642
DOI: 10.1038/s42003-021-02368-8
Popis: Hui-Qi Qu et al. present a case-control association study to examine the genetic architecture of European patients with type 1 diabetes (T1D) of low genetic risk score. They identify 41 loci associated with T1D of low genetic risk score, including regions previously linked to viral infection and autism spectrum disorder, altogether providing further insight into the pathogenesis of T1D.
Databáze: Directory of Open Access Journals