| Autor: |
Naser Hajavi, Khatereh Isazadeh Far, Moharram Eslami, Afshin Habibzadeh, Mehdi Hemmati, Crystal Lu |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
Erciyes Medical Journal, Vol 41, Iss 2, Pp 153-157 (2019) |
| Druh dokumentu: |
article |
| ISSN: |
2149-2247 |
| DOI: |
10.14744/etd.2019.34445 |
| Popis: |
Objective: In this study, we evaluated the efficacy of NAC in dyspepsia symptoms in Helicobacter pylori (H. pylori) negative dyspeptic patients. Materials and Methods: In this randomized clinical trial, 85 patients with functional dyspepsia without H. pylori infection underwent treatment with a proton pump inhibitor (PPI) pantoprazole 40mg daily (n=41) with or without NAC 600mg twice a day (n=44) for 8 weeks. Patients' clinical symptoms and change in the severity of dyspepsia symptoms were compared between the groups. Results: Common symptoms were epigastric pain and bloating. The intervention group had significantly more cases with retrosternal burn and bloating and less early satiety as compared to the control group. In both intervention and control groups dyspepsia severity was significantly reduced from 5.26+-2.06 and 4.68+-2.81 to 1.87+-1.38 and 2.22+-2.04, respectively (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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