APPLICATION OF NMR IN THE INVESTIGATION OF DYNAMIC TAUTOMERISM OF 4(3H)-QUINAZOLINONE SYSTEM

Autor: Pham Thi Thanh My, Chu Dinh Kinh, Thanh Thi Thu Thuy, Nguyen Ngoc Vinh, Nguyen Thi Phuong Chi
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: ASEAN Journal on Science and Technology for Development, Vol 25, Iss 2, Pp 445-455 (2017)
Druh dokumentu: article
ISSN: 0217-5460
2224-9028
DOI: 10.29037/ajstd.275
Popis: Tautomerism of 4(3H)-quinazolinone system with [(2-hydroxyphenyl)methylene]-2-(4oxoquinazolin-3(4H)-yl)acetohydrazide and N’-[(1E)-(4-hydroxy-3-methoxyphenyl)methylene]-2-(4-oxoquinazolin-3(4H)-yl)acetohydrazide as two representative compounds was investigated on the basis of 1H NMR method at coalescence with the help of line formprogramme. The dynamic parameters such as k, Ea, DG*, DH*, DS* were fully calculated with high reliability.
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