Autor: |
Xue Pan, Xinyue Zhang, Xinyi Wu, Yue Zhao, Yilong Li, Zitong Chen, Yue Hu, Xuezhao Cao |
Jazyk: |
angličtina |
Rok vydání: |
2024 |
Předmět: |
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Zdroj: |
Lipids in Health and Disease, Vol 23, Iss 1, Pp 1-10 (2024) |
Druh dokumentu: |
article |
ISSN: |
1476-511X |
DOI: |
10.1186/s12944-024-02195-w |
Popis: |
Abstract Background Obstructive Sleep Apnea (OSA) is a widespread sleep disturbance linked to metabolic and cardiovascular conditions. The Non-High-Density Lipoprotein Cholesterol to High-Density Lipoprotein Cholesterol Ratios (NHHR) has been proposed as being a potential biomarker to gauge cardiovascular risk. However, its relationship with OSA remains unclear. Methods This survey investigated the link NHHR to OSA in American citizens aged 20 and older using information collected via the National Health and Nutrition Examination Survey (NHANES) during the years 2017 to 2020. Logistic regression models with multivariable adjustments were employed to assess this relationship. Nonlinear associations were explored using smooth curve fitting, with a two-part linear regression model identifying a threshold effect. Subgroup analyses were conducted to evaluate population-specific differences. Results The survey encompassed 6763 participants, with an average age of 50.75 ± 17.32. The average NHHR stood at 2.74, accompanied by a standard deviation of 1.34, while the average frequency of OSA was 49.93%. Upon adjusting for covariates, each unit increase in NHHR may be associated with a 9% rise in OSA incidence. (95% confidence intervals 1.04–1.14; P |
Databáze: |
Directory of Open Access Journals |
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