Synthesis, characterization and In-vitro studies of CNT/Gd2O3 hybrid structure

Autor: Rima Paul, Dipanwita Chatterjee, Lopamudra Das Ghosh, Venkatesha Narayanswamy, Mahander Pratap Singh, Manish Agarwal, Deepshikha Ghosh, Mithun Radhakrishna, Chandra Sekhar Tiwary, Ivo Provazník, Kamanio Chattopadhyay
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Carbon Trends, Vol 11, Iss , Pp 100272- (2023)
Druh dokumentu: article
ISSN: 2667-0569
DOI: 10.1016/j.cartre.2023.100272
Popis: Carbon nanotubes have been explored in various fields of science and technology due to their unique properties. However, their toxic nature put limitations to its consideration for the bio-medical applications. In our work, we report the synthesis of paramagnetic CNT/Gd2O3 hybrid nanostructures through easily scalable electrochemical deposition technique. The nanostructure has shown significant longitudinal relaxivity of 18.93 mM−1s−1 for water protons indicating its possibility to be used as an MRI contrast agent. The in-vitro cytotoxicity test on the normal (HaCaT) and cancerous (HeLa) cells reveal that CNT/Gd2O3 hybrid nanostructure is bio-compatible in comparison to the pure CNTs, which is further supported by our theoretical studies using MD simulations.
Databáze: Directory of Open Access Journals