Maternal and neonatal outcomes of intrahepatic cholestasis of pregnancy after in vitro fertilization

Autor:	Ying Zhu, Le Xu, Rajluxmee Beejadhursing, Fei Li
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	Intrahepatic cholestasis of pregnancy In vitro fertilization Maternal complications Neonatal outcomes Gynecology and obstetrics RG1-991
Zdroj:	BMC Pregnancy and Childbirth, Vol 24, Iss 1, Pp 1-5 (2024)
Druh dokumentu:	article
ISSN:	1471-2393
DOI:	10.1186/s12884-024-06248-x
Popis:	Abstract Background Intrahepatic cholestasis of pregnancy (ICP) is an idiopathic disease of pregnancy. Little is known about how it specifically affects pregnancies resulting from in vitro fertilization (IVF). Our aim is to evaluate the impact of IVF on the perinatal outcomes of ICP. Methods A retrospective study of 242 patients with intrahepatic cholestasis of pregnancy, comprising 36 conceived through IVF and 206 spontaneous conceptions (SC), enrolled between 2019 and 2021 was carried out. Data were analyzed from the medical archives of the Huazhong University of Science and Technology, Tongji Hospital. Results Numerical values of transaminases (ALT, alanine aminotransferase; AST, aspartate aminotransferase) and serum total bile acid (TBA) are significantly lower in the IVF group than that in the spontaneous conceived group (p
Databáze:	Directory of Open Access Journals
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