DIAGNOSTIC SIGNIFICANCE AND DETERMINATION OF C-REACTIVE PROTEIN (CRP) IN ADULT PATIENTS WITH COMMUNITY ACQUIRED PNEUMONIA
| Autor: | Jawed Altaf Baig, Junaid Mahmood Alam, Zia ul Islam, Amna Hussain, Sarah Sughra Ashgar, Syed Riaz Mahmood |
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| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: | |
| Zdroj: | Khyber Medical University Journal, Vol 5, Iss 4, Pp 185-189 (2013) |
| Druh dokumentu: | article |
| ISSN: | 2305-2643 2305-2651 |
| Popis: | Objective: to study the diagnostic significance and determination of serum C-reactive protein (CRP) levels in patients with community acquired pneumonia (CAP) at the time of diagnosis and compared it with CRP of healthy controls. Methodology: This study was conducted from December 2005 to Dec 2009 on 162 adult patients and 30 (males=15, females=15) healthy controls. All microbiological assays were performed according to standardized procedures; whereas CRP was measured in serum samples by an automated turbidimetric method with normal reference of ≤ 5.0 mg/L. Results: A total of 85 patients (52.46%) had an identifiable etiology with bacterial pathogens as the causative agents, 31 (19.31%) had viral origin, 10 (6.17%) had other bacterial pathogens and 36 patients (22.22%) with negative microbiological findings. Mean serum CRP levels were 101±15.60 mg/L, 84.50±12.60 mg/L,76.50±11.60 mg/L and 90.35±11.50 mg/L, 85.10±10.15 mg/L & 79.10±15.20 mg/L for Klebsiella pneumonia, Streptococcus pneumonia, Haemophilus influenzae alone and in combination with other pathogens respectively. Mean serum CRP was 60.45±9.10 mg/L in viral etiology only and 4.10 ± 2.25 mg/L in controls. CRP values were comparable in different etiologic groups of bacterial origin, except Streptococcus pneumoniae and Klebsiella pneumoniae groups (P |
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