Characterization of rickettsia rickettsii in a case of Fatal Brazilian spotted fever in the city of Rio de Janeiro, Brazil

Autor:	Cristiane Lamas, Alexsandra Favacho, Tatiana Rozental, Márcio N. Bóia, Andrei H. Kirsten, Alexandro Guterres, Jairo Barreira, Elba Regina S. de Lemos
Jazyk:	angličtina
Předmět:	Brazilian spotted fever spotted fever group rickettsia Rickettsia rickettsii lethal case Rio de Janeiro city indirect immunofluorescence polymerase chain reaction central nervous system involvement Infectious and parasitic diseases RC109-216 Microbiology QR1-502
Zdroj:	Brazilian Journal of Infectious Diseases, Vol 12, Iss 2, Pp 149-151
Druh dokumentu:	article
ISSN:	1678-4391 1413-8670
DOI:	10.1590/S1413-86702008000200010
Popis:	A lethal case of Brazilian spotted fever (BSF) is presented. Clinical features were initially of gastrointestinal involvement and evolved with progression to septic shock, meningoencephalitis and death on the 6th day of illness. Indirect immunofluorescence assay (IFA) for spotted fever group rickettsia (SFGR) was non-reactive. Diagnosis was confirmed by the polymerase chain reaction (PCR) and the nucleotide sequencing of a fragment of the ompA gene showed 100% homology to Rickettsia rickettsii. BSF has not been reported in the city of Rio de Janeiro in the last three decades, and the present description should alert the clinicians to its presence in urban Rio de Janeiro, and to the differential diagnosis with dengue fever, gastroenteritis, leptospirosis and bacterial septic shock, among others.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/293cde06f1f24fa8a9549c2b07f5f172 Zobrazit plný text záznamu View record in DOAJ